• Triple Lipid-Peptide Cream Texture Swatch Image
  • Triple Lipid-Peptide Cream Action Image
  • Triple Lipid-Peptide Cream Refill Action Image
  • Skinfix moisturizer guide showing Triple Lipid-Peptide Cream for dry to normal skin, Ceramide Prime Whipped Cream for normal to combination skin, and Barrier Balancing Water Cream for combination to oily skin.
  • Triple Lipid-Peptide Cream New Packaging Image
  • Triple Lipid-Peptide Cream Refill Hero Image
  • Triple Lipid-Peptide Cream Jumbo Hero Image
  • Triple Lipid-Peptide Cream Mini Hero Image
Bestseller

Triple Lipid-Peptide Cream

Re-meet the original formula of this derm-approved must-have.

Most moisturizers mask dryness at skin’s surface. This one—powered by clinically proven ingredients like ceramides and peptides—amplifies your skin’s ability to retain moisture instantly and over time by rebuilding its protective barrier. 

Benefits

  • Hydrates
  • Smooths
Size

Get 2 free samples with all orders

Free shipping on orders over $50

Triple Lipid-Peptide Cream

  • Triple Lipid-Peptide Cream Texture Swatch Image
  • Triple Lipid-Peptide Cream Action Image
  • Triple Lipid-Peptide Cream Refill Action Image
  • Skinfix moisturizer guide showing Triple Lipid-Peptide Cream for dry to normal skin, Ceramide Prime Whipped Cream for normal to combination skin, and Barrier Balancing Water Cream for combination to oily skin.
  • Triple Lipid-Peptide Cream New Packaging Image
  • Triple Lipid-Peptide Cream Refill Hero Image
  • Triple Lipid-Peptide Cream Jumbo Hero Image
  • Triple Lipid-Peptide Cream Mini Hero Image

Full 1.7 oz

A buttery rich barrier cream that amplifies hydration instantly and over time

A buttery rich barrier cream that amplifies hydration instantly and over time

Woman applying cream to her face with a neutral background
  • Do No Harm
    Details
    • Clinically Tested
    • Dermatologist Tested
    • Safe for Sensitive Skin
    • Non-Comedogenic
    • Non-Irritant
    • Hypoallergenic
    • Vegan
    • Cruelty-Free
    Refills

    Restock with a refill pod to save 80% of plastic compared to repurchasing the full size Triple Lipid-Peptide Cream. The refill pod won’t fit the mini 0.5 oz. jar or the XL 3.3 oz. jar.

  • Do No Harm
    Details
    • Clinically Tested
    • Dermatologist Tested
    • Safe for Sensitive Skin
    • Non-Comedogenic
    • Non-Irritant
    • Hypoallergenic
    • Vegan
    • Cruelty-Free
    Refills

    Restock with a refill pod to save 80% of plastic compared to repurchasing the full size Triple Lipid-Peptide Cream. The refill pod won’t fit the mini 0.5 oz. jar or the XL 3.3 oz. jar.

  • Ingredients
    3% Triple Lipid Complex

    Ceramides, sterols and fatty acids mimic skin's barrier to lock in moisture

    3% Peptide Solution

    Barrier-repair protein-builders that weightlessly help skin retain moisture

    8% Humectant Blend

    Hyaluronic acid, glycerin, and red algae deposit instant, lasting hydration

    Free From

    × fragrance
    × essential oils
    × silicones
    × phthalates
    × microplastics
    × parabens
    × sulfates
    × PEGs
    × gluten

  • Ingredients
    3% Triple Lipid Complex

    Ceramides, sterols and fatty acids mimic skin's barrier to lock in moisture

    3% Peptide Solution

    Barrier-repair protein-builders that weightlessly help skin retain moisture

    8% Humectant Blend

    Hyaluronic acid, glycerin, and red algae deposit instant, lasting hydration

    Free From

    × fragrance
    × essential oils
    × silicones
    × phthalates
    × microplastics
    × parabens
    × sulfates
    × PEGs
    × gluten

  • How to Use
    Day + Night
    • Apply 1-2 pumps to clean, dry skin after serum and eye cream
    • Use every day, twice a day—in the morning and at night
    Lock it In

    Apply makeup while moisturizer still feels wet for a boost of dewiness

    Good to Know

    Plays well with actives—like exfoliating acids, retinoids, and brighteners

  • How to Use
    Day + Night
    • Apply 1-2 pumps to clean, dry skin after serum and eye cream
    • Use every day, twice a day—in the morning and at night
    Lock it In

    Apply makeup while moisturizer still feels wet for a boost of dewiness

    Good to Know

    Plays well with actives—like exfoliating acids, retinoids, and brighteners

  • Awards
    2025

    Good Housekeeping Beauty Award winner for Genius Anti-Agers

    2024

    WWD - The Greatest Skincare

    2022

    Shape Skin Award

    2022

    Skin Anarchy Top Picks - Moisturizer

    2022

    Prevention Beauty Award Winner - Best Face Moisturizer

    2021

    Women's Health Best of Skincare Award Winner

    2019

    Allure Best of Beauty Award Winner

    2025

    Allure Best of Beauty Award Winner - Best Clean Skincare

  • Awards
    2025

    Good Housekeeping Beauty Award winner for Genius Anti-Agers

    2024

    WWD - The Greatest Skincare

    2022

    Shape Skin Award

    2022

    Skin Anarchy Top Picks - Moisturizer

    2022

    Prevention Beauty Award Winner - Best Face Moisturizer

    2021

    Women's Health Best of Skincare Award Winner

    2019

    Allure Best of Beauty Award Winner

    2025

    Allure Best of Beauty Award Winner - Best Clean Skincare

See in Action
  • Before Close-up of a person’s cheek with dotted circles highlighting areas of uneven skin tone and texture.
    After Close-up of the same person’s cheek after use, with dotted circles highlighting changes in the appearance of skin tone and texture.
  • Before Close-up of a person’s cheek with a dotted circle highlighting visible redness and skin texture.
    After Close-up of the same person’s cheek after use, with a dotted circle highlighting changes in the appearance of redness and skin texture.
  • Before Close-up of a person’s cheek with dotted circles highlighting uneven skin tone and skin texture.
    After Close-up of the same person’s cheek after use, with dotted circles highlighting changes in the appearance of skin tone and texture.

Clinical Results

Clinically proven to deliver glowier (+26%), smoother (+29%) and firmer (+12%) skin after 4 weeks
Results of a 4-week clinical trial on 35 subjects, analyzed with expert clinical grading, after 4 weeks

  • 100% showed improved moisture retention, with hydration increasing by 46% immediately and 67% after 4 weeks

    Results of a 4-week clinical trial on 35 subjects, analyzed with a vapometer and corneometer, immediately and after 4 weeks

  • 100% said their skin feels smoother and deeply hydrated

    Results of a 4-week consumer perception study on 35 subjects, after 1 week

  • 100% had immediate barrier function improvement

    Results of a 4-week clinical trial on 35 subjects, analyzed with a vapometer, immediately

Environmental

Reducing our impact is important to us

We partnered with Bluebird to complete a full Life Cycle Analysis on the carbon and waste impact of this product.

Reducing our impact is important to us

We partnered with Bluebird to complete a full Life Cycle Analysis on the carbon and waste impact of this product.

Production

Made in North America with ethical labor practices

Box

100% FSC certified paper made with 30% recycled fibres and plant-based inks

Partners
Learn more about our sustainability commitments
  • Jar

    Unscrew the regular size 1.7 oz base and reuse it with the refill, or remove the pump and replace the cap on the base, then place it in the recycle bin. 

    *The refill pod won't fit the mini 0.5 oz jar or the XL 3.3.oz jar. 

    Packaging Facts

    1.7 oz: 70% PCR PP outer Jar. 44% PCR PP by weight inner pod.
    0.5 oz: 50% PCR PP Jar

  • Pump

    Save the pump and reuse it with the refill, or place it in the Pact Collective bin for recycling - locations here

    Packaging Facts

    26% PCR mixed material

  • Cap

    Save the cap to reuse with the refill component, or snap it back on base to place in the recycle bin

    Packaging Facts

    1.7 oz: 70% PCR
    0.5 oz: 50% PCR PP

  • Box

    Place in recycle bin

    Packaging Facts

    100% FSC certified paper made with 30% recycled fibres and plant-based inks
  • Step 1

    Unscrew pump from jar and remove empty pod–white disc included

  • Step 2

    Open refill pod and remove foil seal

  • Step 3

    Place refill in base jar, screw pump onto base, and prime for use

FAQ

  • Is this safe for sensitive and/or eczema prone skin?

    Yes! Triple Lipid-Peptide Cream is clinically proven to be safe for sensitive skin and is formulated without common irritants, making it a great option for eczema-prone skin too. It’s rich in barrier-supporting ingredients to help keep skin calm, hydrated, and resilient.

  • Is this safe for acne-prone skin?

    Triple Lipid-Peptide Cream was tested to be non-comedogenic and is safe for acne-prone skin. It can be especially helpful if you’re using prescription acne treatments, since it restores the moisture they can deplete. That said, it was developed with dry skin in mind—if you're acne-prone and tend to be more combo or oily, we’d recommend trying our Barrier Balancing Water Cream instead. Water Cream is a better option if you're prone to fungal acne, too.

  • Can I layer this with actives?

    Triple Lipid-Peptide Cream was formulated with hydrating, barrier-supporting ingredients, so it layers well with most actives—including retinoids, vitamin C, AHAs, BHAs and prescription topicals. Its soothing formula can actually help buffer potential irritation, making it a great companion product in your routine. As always, if you’re trying a new combination for the first time, we recommend patch testing or introducing products gradually to see how your skin responds.

  • Is this safe to use during pregnancy and breastfeeding?

    Triple Lipid-Peptide Cream has been reviewed and tested for safety on a panel of people who aren’t pregnant or breastfeeding. It does not include any ingredients known to be unsafe while pregnant or breastfeeding, but as with any new product, we recommend checking with your healthcare provider if you're concerned.

Overall rating: 4.760023 / 5 from 3442 reviews.

AI Generated Review Summary

This Triple Lipid-Peptide Cream is highly praised for its ability to deeply hydrate and improve skin texture, with quick absorption and a rich formula. While some customers appreciate its soft feel and environmentally friendly packaging, opinions on the scent are mixed.

Summary topics

  • Skin Feel: 21%
  • Absorption Speed: 6%
  • Product Texture: 7%
  • Product Formula: 4%
  • Skin Appearance: 7%

Review topics: ["acne","color","breakouts","press","ingredients","irritation","size","fit","fragrance","spots","redness","scent","wrinkles","thickness","pimples","retinol","results","neck","bumps","dryness","pores","eyes","dose","cleanser","protection","skin","weight","exfoliation","relief","improvement"].

Review highlights

  • "This cream feels rich and luxurious, yet it absorbs well without leaving my skin greasy." — brandon
  • "My skin absorbs the cream easily, leaving it feeling soft and hydrated." — rachelramras
  • "This cream really works well for my dry skin, I love the texture and the fact that it absorbs really quickly." — indigirlrviews

Reviews

I like the airless pump.

"I like the airless pump. May it does not lose efficacy halfway down the jar if it is open at the top, which this is not unlike most of the creams that you buy in the department store. It is also similar to a high quality high priced skin care product called SkinCeuticals, which I have used and understand this has very similar ingredients so 10 points for that I’m impressed."

— Cynthia P. (5/5)

I usually stay away from

"I usually stay away from ‘influencer’ recommendations, especially when they are ‘obsessed’…. . but I caved and got this for my dry, sensitive and somewhat reactive skin - and I have to admit that this cream is amazing. Excellent performance, lovely feel, great container and appreciate that you can buy refills! This MADE me buy other products from Skinfix (serum and eye cream) which are equally as impressive!"

— Krystle G. (5/5)

I've been using this face

"I've been using this face cream now for about a year I believe (maybe more) and I can say that I do not see myself switching over anytime soon. I have oily-combo skin. However, my skin is incredibly sensitive. Skinfix products seem to do wonders for me. Never leave me irritated and are very hydrating"

— Gabriela R. (5/5)

My favorite lightweight hydrating cream!

"My favorite lightweight hydrating cream! I have dry/ combo skin and this cream is so nice and light. I use about the size of a blueberry or less and it spreads evenly throughout my face/ neck. My skin feels so much better since switching to this line and fixing my barrier."

— Alysia O. (5/5)

Been using this since 2021,

"Been using this since 2021, and it has been a staple in my routine since. They have made some significant changes to size, packaging, etc. and it's only gotten better in my opinion. Even the size/amount that comes out has changed subtly in good way. Hope they maintain this formula for a while."

— Liza C. (5/5)

A little too rich for

"A little too rich for my reactive skin but have loved some of their other products. I may go for something a bit lighter next time."

— Amanda B. (3/5)

My new favourite

"The peptide cream is my go-to product though, and I am already on my 3rd repurchase. It absorbs quickly, calms my skin, and my face still feels moisturized in the morning. Love, love, love and will keep buying this product over again!"

— Lisa (5/5)

I decided to try this

"I decided to try this moisturizer since my regular Sunday Riley one has been sold out. I am pleasantly surprised by this moisturizer! It’s thick, but not too thick. It absorbs well, and it keeps my skin hydrated. I’ve only incorporated it in my nighttime routine, and my skin seemed to transition very well to this. I like the dispenser too. I feel like it allows the perfect amount of moisturizer at a time."

— AMANDA P. (5/5)

So grateful for refills for

"So grateful for refills for my beloved Triple Peptide Cream. This is rich and soothing and the perfect night and day moisturizer. The packaging keeps it hygienic and easy to dispense."

— Caroline D. (5/5)

Love this stuff, it is

"Love this stuff, it is measured out perfectly with the container, and beyond that it has my skin glowing, smooth, and keeps me looking young and I just love it. Will keep using it for good I believe, it's my favorite code to not looking old. Thank you Skinfix!"

— Bradley B. (5/5)

Q&A

Is this cream fungal safe?
Hi May, The lipid rich formulation is not fungal acne safe. Our barrier+ Barrier Balancing Water Cream is though!! https://skinfix.com/products/barrier-balancing-water-cream
Vegetable oil is listed in the ingredient list, but it does not specify which plant oil is used. Vegetable oil can rate 0-5 on the comedogenic scale. I realize the Triple Lipid cream is advertised as non-comedogenic, but I am very acne prone even though I have dry skin. It is not oily. Can you provide a more specific description of what plant your vegetable oil is sourced from?
Hi Anne, In cosmetics, “vegetable oil” usually refers broadly to oils derived from plants—like soybeans, sunflowers, or palm—not kitchen vegetables like corn or carrots. Ours is a cosmetic-grade, hydrogenated blend of natural triglycerides from 100% vegetable origin. It’s been processed and purified specifically for skin care use—to help condition and soften the skin. We totally understand your concern. While ingredients like hydrogenated vegetable oil may sound heavy or pore-clogging on their own, comedogenicity really depends on the overall formulation—not just a single ingredient in isolation. Our Triple Lipid-Peptide Cream was clinically tested and confirmed to be non-comedogenic, meaning it did not clog pores or cause breakouts. The formula is carefully balanced with barrier-repairing lipids and soothing hydrators to be safe and effective for all skin types, including those prone to congestion.
I'm seeing any peptides listed in the ingredients. What are they called here?
Hi Michelle, Thank you for your question. We list ingredients by their INCI (International Nomenclature of Cosmetic Ingredients) names, which can definitely be a little confusing! Peptides are short chains of amino acids—the building blocks of proteins—and the ones we use in Triple Lipid-Peptide Cream are rice-derived. On the ingredient list, you’ll see them listed as Hydrolyzed Rice Protein. So even though it doesn’t have “peptide” in the name, rest assured it still functions as one in the formula.
Can dry/combo skin use this?
Hi Zion, Thanks for reaching out. Our barrier+ Triple Lipid-Peptide Cream is our holy grail for those who want a lipid rich formulation. This was created for those who need the most hydration, is non comedogenic, so all skin types can use this. Please feel free to reach out to info@skinfix.com if you have any other questions or take our skin quiz if need some guidance on what products are best suited for you: https://ca.skinfix.com/pages/quiz
If I order this product during the summer, will shipping in the heat or having the box left in a community mailbox in the heat damage the product?
Hi Galus, Thank you for your question- We temperature test all of our products for both extreme cold and heat, to ensure it is stable and able to withstand the many different weather conditions for North America. This should not have any bearing on when you order and how it ships during the summer. If you are concerned, you can also purchase our products at your local Sephora store-we hope this helps!
Does the mini version have a pump like the standard size, or is it just open on top?
Hi Erin, Thank you for reaching out- the mini Triple Lipid-Peptide Cream does not have a pump. It is an open jar to dispense with clean fingers. We hope this helps!
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